Effect of computer radiation on weight and oxidant-antioxidant status of mice.

OBJECTIVES To explore the effects of computer radiation on weight and oxidant-antioxidant status of mice, and further to confirm that whether vitamin C has protective effects on computer radiation. METHODS Sixty Male adult ICR mice were randomly divided into six groups. each group give different treatment as follows: group A was control, group B given vitamin C intake, group C given 8 h/day computer radiation exposure, group D given vitamin C intake and 8 h/day computer radiation group E given 16 h/day computer radiation exposure, group F given vitamin C intake plus exposure to 16 h/day computer radiation. After seven weeks, mice was executed to collect the blood samples, for detecting total antioxidant capacity (T-AOC) and alkaline phosphatases (ALP)content in serum or liver tissue were determined by ELISA. RESULTS No difference was found for the change of weight among six groups at different week. In the group C, D and F, the liver tissue T-AOC level were higher than the group A. In the group B, C and E, the serum ALP level were lower than the group A (P<0.05). CONCLUSIONS The study indicate that computer radiation may have an adverse effect on T-AOC and ALP level of mice, and vitamin C have protective effect against computer radiation.